CLINICAL PHENOMENOLOGY OF TIC DISORDERS IN CHILDREN: A SERIES OF CLINICAL CASES
Keywords:
TICs, Tourette's syndrome, children, hyperkinesis, cognitive behavioral therapy, antipsychotics.Abstract
TIC disorders in children are a common neurological pathology, ranging from transient benign forms to chronic and disabling ones, such as Gilles de la Tourette syndrome (CJT). The article presents three typical clinical cases reflecting the spectrum of tic hyperkinesis: Transient tics in a 7-year-old child with complete regression on the background of non-drug correction. Chronic motor tics in a 9-year-old girl who required a combination of cognitive behavioral therapy and pharmacotherapy. Gilles de la Tourette syndrome in a 12-year-old boy with comorbid psychiatric disorders, demonstrating the need for a multidisciplinary approach. Special attention is paid to differential diagnosis, the role of stress factors, as well as modern treatment methods, including behavioral techniques (habit reversal training), pharmacotherapy (clonidine, risperidone) and psychosocial support. The importance of early intervention to improve the prognosis and quality of life of patients is emphasized.
References
Alves, H.L.; Quagliato, E.M. The prevalence of tic disorders in children and adolescents in Brazil. Arq Neuropsiquiatr. 2014, 72(12):942-948. doi:10.1590/0004-282X20140174
Bloch, M.H.; Peterson, B.S.; Scahill, L.; Otka, J.; Katsovich, L.; Zhang, H.; Leckman, J.F. Adulthood outcome of tic and obsessive-compulsive symptom severity in children with Tourette syndrome. Arch Pediatr Adolesc Med. 2006, 160(1):65-69. doi:10.1001/archpedi.160.1.65
Chutko, L.S.; Surushkina, S.Yu.; Anisimova, T.I. Emotional disorders in adolescents with Tourette syndrome and their mothers. S.S. Korsakov Journal of Neurology and Psychiatry. 2018, 118(11):56-59. doi:10.17116/jnevro201811811156
Kadesjö, B.; Gillberg, C. Tourette's disorder: epidemiology and comorbidity in primary school children. J Am Acad Child Adolesc Psychiatry. 2000, 39(5):548-555. doi:10.1097/00004583-200005000-00007
Khalifa, N.; von Knorring, A. Prevalence of tic disorders and Tourette syndrome in a Swedish school population. Developmental Medicine & Child Neurology. 2003, 45:5. doi:10.1017/s0012162203000598
Kurvits, L.; Martino, D.; Ganos, C. Clinical features that evoke the concept of disinhibition in Tourette syndrome. Front Psychiatry. 2020, 11(21):21. doi:10.3389/fpsyt.2020.00021
Li, F.; Cui, Y.; Li, Y.; Guo, L.; Ke, X.; Liu, J. et al. Prevalence of mental disorders in school children and adolescents in China: diagnostic data from detailed clinical assessments of 17,524 individuals. J Child Psychol Psychiatry. 2022, 63:34–46. doi:10.1111/jcpp.13445
Nurmatova, D.A.; Zhukova, N.G.; Sayfitdinkhuzhaev, Z.F.; Okhunbaev, J.M. Morphometric Characteristics of Cerebral Structures in Gilles De La Tourette Syndrome. Personalized Psychiatry and Neurology. 2025, 5(1):2-9. https://doi.org/10.52667/2712-9179-2025-5-1-2-9
Surén, P.; Bakken, I.; Skurtveit, S.; Handal, M.; Reichborn-Kjennerud, T.; Stoltenberg, C.; Nøstvik, L.; Weidle, B. Tidsskr Nor Laegeforen. 2019, 139(17). doi:10.4045/tidsskr.19.0411
Yu, L.; Xu, H.; Jiang, Z.; Yang, H.; Cui, Y.; Li, Y. Comorbidity of physical illnesses and mental disorders in outpatients with tic disorders: a retrospective study using the outpatient care system. Front Neurol. 2024, 15:1397766. doi:10.3389/fneur.2024.1397766
